... reduced in all joints, thus indicating anomalies not only in hand opening but also in hand closing However, peak speed reached during hand closing was significantly higher than that obtained during ... both in hand opening and closing Analysis of the temporal aspects of hand motion revealed two typical inter-joint coordination patterns in hand opening and closing respectively During hand opening, ... identify the initiation and termination of hand opening and closing separately The initiation time of hand opening/closing (T start ) was defined as the instant in which the first joint reached...
... tool for studying reaching and grasping in healthy subjects and in individuals with hemiparesis by comparing movement kinematics of identical tasks made in a physical and a virtual environment Since ... Levin MF: Interjoint coordination during pointing movements is disrupted in spastic hemiparesis Brain 1996, 119:281-293 Michaelsen SM, Levin MF: Short-term effects of practice with trunk restraint ... movement task for one healthy subject Mean endpoint of conditions index finger) trajectories for Mean endpoint (marker on the index finger) trajectories for the two phases of the movement task for one...
... retinacular tenderness in patients with patellofemoral pain, including some who demonstrated histological changes within the perineural tissues of the lateral retinaculum on examination of surgical ... imbalance [21] Introduction Patellofemoral pain syndrome (PFPS) presents one of the most perplexing pathologic conditions in orthopedic and sports medicine clinics, as well as in rehabilitation ... alter the tracking of the patella in the trochlear groove, becoming an important factor in the etiology of patellofemoral pain [37] Following this theory, some clinicians contraindicate rehabilitation...
... MCA in baseline conditions and in correspondence of the maximum CBFV increase during the apnea The PI is defined according to the following expression: PI = PV − EDV MV ( 3) This parameter indicates ... this difficulty, we preliminary instructed the subjects on how to perform the BH and we let them test the procedure once before starting the recordings In particular, we instructed the subjects ... derive baseline conditions, the subjects were allowed to rest for about 10 minutes in a dimmed and quiet room, laying comfortably in a supine position with eyes closed and breathing room air;...
... School of Medicine approved the experiments Subjects were free from treatment for past psychiatric illness Written informed consent was obtained after the procedure had been fully explained In the ... on a semi-reclined chair in a sound-attenuated and electrically shielded room during recordings Subjects were instructed to press a button as quickly as possible upon hearing the infrequent high-pitched ... repeated testing, but not effects of drug group, on test scoring without a significant interaction in some tests including trail making A (F (1,16) = 7.399, P = 0.0151, Figure 3a), trail making B (F...
... pool of B cells that had completed their differentiation into antibody-secreting plasma cells before abatacept was administered Abatacept prevents the activation of naive T cells by inhibiting the ... the log of the baseline (prevaccination) antibody level as the covariate For each antibody, point estimates and 95% confidence intervals for the prevaccination to postvaccination changes on the ... ethical principles of the Declaration of Helsinki and was approved by Institutional Review Boards All subjects gave informed consent Drug administration and vaccination Abatacept 750 mg was administered...
... Vitamin C Vitamin E aChange (mm3) in tibial cartilage volume per standard-deviation increase in vitamin C/vitamin E intake before and after adjusting for energy intake, age, gender, body mass index, ... being present per standard-deviation increase in vitamin C/vitamin E intake before and after adjusting for energy intake, age, gender, body mass index, and tibial cartilage volume cChange in ... standard-deviation increase in vitamin C/vitamin E intake before and after adjusting for energy intake, age, gender, and body mass index dOdds ratio of tibiofemoral bone marrow lesions being present...
... contributing to neovascularization Cytokines seem to be involved in the mobilization of BM-EPCs [10] Systemic administration of hepatocyte growth factor (HGF), a multifunctional cytokine involved in ... consent form Simulated altitude (normobaric hypoxia) Subjects set quietly breathing room air for five minutes before breathing an oxygen mixture at 11.2% (corresponding to 4850 m) for h by using ... activation has a principal rolein host defence, recent studies also demonstrate that endothelial cells are capable of complex molecular responses against various forms of stress including hypoxia Hypoxic...
... Detection System: 95°C for 10 minutes, followed by 40 cycles at 95°C for 15 seconds and 60°C for minute To determine genotypes, end-point fluorescence was read on the 7900 HT Sequence Detection Systems ... YKL-40 with the remaining SNPs could be explained by LD Our findings indicate that serum concentrations of YKL-40 are under the influence of genetic variability in the CHI3L1 gene in both patients ... Ahangari F, Ma B, Kang MJ, He CH, Takyar S, Elias JA: Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling and injury Ann Rev Physiol 2011, 73:479-501 Faibish M,...
... SF-36 Item % Missing Mean SD Physical Functioning (PF) Vigorous activities Walking more than a kilometer Climbing several flights of stairs Bending, kneeling, stooping Lifting or carrying groceries ... cataract)" 3In response to the question "Do your teeth currently cause you ", ticking "yes" to any of the conditions "discomfort speaking", "discomfort swallowing", "discomfort chewing" or "pain" discriminate ... percent of missing data in every item and the frequency distribution of individual items were determined Ordering of levels of health The ordering of item means within its scale was examined and compared...
... controls In a recent study by Viau [9], a VR task was validated as a tool for studying arm movements in healthy and stroke subjects by comparing movement kinematics in a virtual environment and in ... thumb against the four fingers The procedure was standardized concerning sitting position and instructions in each test The subjects were seated comfortably on Page of (page number not for citation ... right hand Data analysis Kinematic data sampling and information processing Hand position data (haptic stylus end-point) were gathered during each trial The x-, y- and z-coordinates, which were time...
... two tracer injections A short indwelling catheter was placed in the non-dominant radial artery under local anaesthesia forblood sampling Page of 10 Image acquisition During scanning, the subject’s ... decay For kinetic modelling, arterial blood was sampled continuously during the scans using an automatic blood sampling system [ABSS] (Allogg, Mariefred, Sweden) set to draw arterial blood at a ... 7min emission scans were acquired in a three-dimensional [3D] list mode and initiated immediately before tracer injection The interscan interval was at least 10 to allow for isotope decay For...
... controls In a recent study by Viau [9], a VR task was validated as a tool for studying arm movements in healthy and stroke subjects by comparing movement kinematics in a virtual environment and in ... thumb against the four fingers The procedure was standardized concerning sitting position and instructions in each test The subjects were seated comfortably on Page of (page number not for citation ... right hand Data analysis Kinematic data sampling and information processing Hand position data (haptic stylus end-point) were gathered during each trial The x-, y- and z-coordinates, which were time...
... draft the manuscript TE was involved in the genetic analyses and was involved in drafting the manuscript KZ was involved in the genetic analyses and was involved in drafting the manuscript MN made ... drafting the manuscript VM was involved in the acquisition of data and was involved in drafting the manuscript MT was involved in the statistical analysis and the interpretation of data and helped ... cognitive functions in healthy individuals per se, but even a positive effect in some cognitive domains (such as verbal working memory and attention) This finding is at first glance counterintuitive,...
... follows: bafilomycin, an inhibitor of endosomal acidification, for 15 min; N-acethyl-Lcysteine was for 10 min; MG-132, a proteosome inhibitor, for 60 min; and dexamethasone for 30 Media were ... School of Medicine Informed written consent was obtained from all subjects Immunocytochemistory 100 μl of the neutrophil suspension containing × 105 cells were centrifuged by a Cytospin cytocentrifuge ... derived from inflammatory cells cause pro-inflammatory cytokine production In fact, H2O2 has been reported to augment cytokine production in previous studies [9,10] Among inflammatory cells, neutrophils...
... CT images showed an increase in poorly aerated areas (reaching 15% of the region of interest); non-aerated areas remained close to zero Such findings suggest an alternative interpretation of the ... before the tests The right femoral vein was also catheterized for drug administration All animals were sedated with a continuous infusion of ketamine (Ketamina; Cristália, São Paulo, Brazil) delivered ... hyperinflation in non-dependent lung areas In fact, the hyperinflated areas appeared in non-dependent lung regions for PEEP values below cmH2O Elastance behaved as expected with descending PEEP...
... When one eats foods containing capsaicin, the burning sensation is elicited by TRPV1-containing peptidergic nociceptors surrounding taste buds in the tongue [16] Capsaicin-induced cough may not ... capsaicin The intragastric administration of capsiate increases adrenalin secretion and oxygen consumption in mice [21,22] In addition, capsiate suppresses T cell activation by inhibiting NF-κB-dependent ... angiotensinconverting enzyme inhibitor-induced cough [31] would argue against this hypothesis In addition, our result showing no gender difference in oral chemesthesis may also conflict with the systemic...
... responses to inhaled citric acid and dyspnea sensation during inspiratory resistive loads All were originally recruited via public postings in and around the Tohoku University School of Medicine campus ... JM: Hyperresponsiveness to tusive stimuli in cigarette smoke-exposed guinea-pigs: a rolefor capsaicinsensitive, calcitonin gene-related peptide-containing nerves Acta Physiol Scand 1991, 141:445-454 ... this In each subject, the estimated urge-to-cough scores were plotted against the corresponding citric acid concentration using a log-log transformation Since it is known that there is a linear...
... situations independent against the stressor, maintaining stability, can of the outcomes, being the effects better or become harmful for health and survival if called upon repeatedly, in the form of ... asteriscs indicate p < 0.05 for the comparisons made between elderly with high and low stress intensity according to coping style Two-way ANOVA Figure - Mean of SSL scores according to coping types ... certain coping style can be effective in on situation but not in another When preparing for a test, for example, focusing the action on coping with the problem is adaptive When awaiting the result,...
... female; BMI, body mass index Study design Individuals performed two maximal exercise tests and five 6-MWT on d (1–2 d apart) according to the following manner: day in the morning: 6-MWT and maximal ... exercise test, and in the afternoon: 6-MWT; day in the morning: 6-MWT, and in the afternoon: 6-MWT; day in the morning: maximal exercise test, and in the afternoon: 6-MWT During all tests, they ... 0.05 and ** P Ͻ 0.01 compared with the following lap or 30-s recording Lap by Lap Walking Speed (m⅐s؊1) 30-s Recordings ˙ V O2 (mL⅐kg؊1⅐min؊1) HR (beats⅐min؊1) 10 11 12 1.63 Ϯ 0.07* 1.65 Ϯ 0.06*...